Is Upstream Bio, Inc. (UPB) a Buy, Sell, or Hold?
NASDAQ : UPB
Upstream Bio, Inc. — Insider Trades
$7.05 USD
-$0.04 (-0.56%)
- Volume
- 21.99K
- Average Volume
- 593.6K
- Market Capitalization
- $383.66M
- P/E Ratio
- -2.43
- Dividend Yield
- 0.00%
- Price Target
- $20.00
- Year High
- $33.68
- Year Low
- $5.85
- Day High
- —
- Day Low
- —
- Payout Ratio
- $0.00
- Current Ratio
- $27.99
Insider Activity Summary (Last 12 Months)
Insiders Buying
22
Insiders Selling
10
Amount of Insider Selling
$10033
UPB Insider Buying/Selling by Quarter
UPB Insider Trading History
| Insider Name | Title | Date | Transaction | Cost | Filing Date |
|---|---|---|---|---|---|
| GRAY MICHAEL | officer: CFO and COO | 2026-06-16 | S-Sale | 6.1 | 2026-06-17 |
| Sutherland Everett Rand | director, officer: Chief Executive Officer | 2026-06-16 | S-Sale | 6.1 | 2026-06-17 |
| Houghton Adam | officer: Chief Business Officer | 2026-06-16 | S-Sale | 6.1 | 2026-06-17 |
| Deykin Aaron | officer: Chief Medical Officer | 2026-06-16 | S-Sale | 6.1 | 2026-06-17 |
| Ambrose Allison | officer: General Counsel | 2026-06-16 | S-Sale | 6.1 | 2026-06-17 |
| Ruddy Marcella K. | director | 2026-06-09 | A-Award | 6.69 | 2026-06-11 |
| Renaud Ronald C JR | director | 2026-06-09 | A-Award | 6.69 | 2026-06-11 |
| Fleming Harold Edward | director | 2026-06-09 | A-Award | 6.69 | 2026-06-11 |
| Beckman Daniella | director | 2026-06-09 | A-Award | 6.69 | 2026-06-11 |
| Ratcliffe Liam | director | 2026-06-09 | A-Award | 6.69 | 2026-06-11 |
| Chimovits Erez | director | 2026-06-09 | A-Award | 6.69 | 2026-06-11 |
| GRAY MICHAEL | officer: CFO and COO | 2026-03-16 | S-Sale | 9.29 | 2026-03-17 |
| Deykin Aaron | officer: Chief Medical Officer | 2026-03-16 | S-Sale | 9.29 | 2026-03-17 |
| Sutherland Everett Rand | director, officer: Chief Executive Officer | 2026-03-16 | S-Sale | 9.29 | 2026-03-17 |
| Ambrose Allison | officer: General Counsel | 2026-03-16 | S-Sale | 9.29 | 2026-03-17 |
| Houghton Adam | officer: Chief Business Officer | 2026-03-16 | S-Sale | 9.29 | 2026-03-17 |
| GRAY MICHAEL | officer: CFO and COO | 2026-01-02 | A-Award | 27.07 | 2026-01-06 |
| GRAY MICHAEL | officer: CFO and COO | 2026-01-02 | A-Award | 0 | 2026-01-06 |
| Deykin Aaron | officer: Chief Medical Officer | 2026-01-02 | A-Award | 27.07 | 2026-01-06 |
| Deykin Aaron | officer: Chief Medical Officer | 2026-01-02 | A-Award | 0 | 2026-01-06 |
| Ambrose Allison | officer: General Counsel | 2026-01-02 | A-Award | 27.07 | 2026-01-06 |
| Ambrose Allison | officer: General Counsel | 2026-01-02 | A-Award | 0 | 2026-01-06 |
| Houghton Adam | officer: Chief Business Officer | 2026-01-02 | A-Award | 27.07 | 2026-01-06 |
| Houghton Adam | officer: Chief Business Officer | 2026-01-02 | A-Award | 0 | 2026-01-06 |
| Sutherland Everett Rand | director, officer: Chief Executive Officer | 2026-01-02 | A-Award | 27.07 | 2026-01-06 |
| Sutherland Everett Rand | director, officer: Chief Executive Officer | 2026-01-02 | A-Award | 0 | 2026-01-06 |
| Renaud Ronald C JR | director | 2025-06-10 | A-Award | 11.59 | 2025-06-12 |
| Chimovits Erez | director | 2025-06-10 | A-Award | 11.59 | 2025-06-12 |
| Ruddy Marcella K. | director | 2025-06-10 | A-Award | 11.59 | 2025-06-12 |
| Beckman Daniella | director | 2025-06-10 | A-Award | 11.59 | 2025-06-12 |
| Fleming Harold Edward | director | 2025-06-10 | A-Award | 11.59 | 2025-06-12 |
| Ratcliffe Liam | director | 2025-06-10 | A-Award | 11.59 | 2025-06-12 |
| Sutherland Everett Rand | director, officer: Chief Executive Officer | 2025-02-06 | A-Award | 8.53 | 2025-02-07 |
| GRAY MICHAEL | officer: CFO and COO | 2025-02-06 | A-Award | 8.53 | 2025-02-07 |
| Houghton Adam | officer: Chief Business Officer | 2025-02-06 | A-Award | 8.53 | 2025-02-07 |
| Deykin Aaron | officer: Chief Medical Officer | 2025-02-06 | A-Award | 8.53 | 2025-02-07 |
| Ambrose Allison | officer: General Counsel | 2025-02-06 | A-Award | 8.53 | 2025-02-07 |
| Ambrose Allison | officer: General Counsel | 2024-12-16 | A-Award | 19.01 | 2024-12-17 |
| Ambrose Allison | 2024-12-16 | 0 | 2024-12-17 | ||
| Chimovits Erez | director, 10 percent owner: | 2024-10-15 | P-Purchase | 17 | 2024-10-17 |
| Chimovits Erez | director, 10 percent owner: | 2024-10-15 | C-Conversion | 0 | 2024-10-17 |
| Chimovits Erez | director, 10 percent owner: | 2024-10-15 | P-Purchase | 17 | 2024-10-17 |
| Chimovits Erez | director, 10 percent owner: | 2024-10-15 | C-Conversion | 0 | 2024-10-17 |
| Chimovits Erez | director, 10 percent owner: | 2024-10-15 | C-Conversion | 0 | 2024-10-17 |
| Chimovits Erez | director, 10 percent owner: | 2024-10-15 | C-Conversion | 0 | 2024-10-17 |
| ORBIMED ADVISORS LLC | director, 10 percent owner: | 2024-10-15 | P-Purchase | 17 | 2024-10-17 |
| ORBIMED ADVISORS LLC | director, 10 percent owner: | 2024-10-15 | C-Conversion | 0 | 2024-10-17 |
| ORBIMED ADVISORS LLC | director, 10 percent owner: | 2024-10-15 | P-Purchase | 17 | 2024-10-17 |
| ORBIMED ADVISORS LLC | director, 10 percent owner: | 2024-10-15 | C-Conversion | 0 | 2024-10-17 |
| ORBIMED ADVISORS LLC | director, 10 percent owner: | 2024-10-15 | C-Conversion | 0 | 2024-10-17 |
| ORBIMED ADVISORS LLC | director, 10 percent owner: | 2024-10-15 | C-Conversion | 0 | 2024-10-17 |
| AI Upstream LLC | 10 percent owner | 2024-10-15 | C-Conversion | 0 | 2024-10-17 |
| AI Upstream LLC | 10 percent owner | 2024-10-15 | C-Conversion | 0 | 2024-10-17 |
| AI Upstream LLC | 10 percent owner | 2024-10-15 | P-Purchase | 17 | 2024-10-17 |
| AI Upstream LLC | 10 percent owner | 2024-10-15 | C-Conversion | 0 | 2024-10-17 |
| AI Upstream LLC | 10 percent owner | 2024-10-15 | C-Conversion | 0 | 2024-10-17 |
| Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | 10 percent owner | 2024-10-15 | C-Conversion | 0 | 2024-10-15 |
| Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | 10 percent owner | 2024-10-15 | C-Conversion | 0 | 2024-10-15 |
| Chimovits Erez | director | 2024-10-10 | A-Award | 17 | 2024-10-15 |
| Ruddy Marcella K. | director | 2024-10-10 | A-Award | 17 | 2024-10-15 |
| Renaud Ronald C JR | director | 2024-10-10 | A-Award | 17 | 2024-10-15 |
| Fleming Harold Edward | director | 2024-10-10 | A-Award | 17 | 2024-10-15 |
| Beckman Daniella | director | 2024-10-10 | A-Award | 17 | 2024-10-15 |
| Ratcliffe Liam | director | 2024-10-10 | A-Award | 17 | 2024-10-15 |
| Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | 10 percent owner | 2024-10-10 | 0 | 2024-10-10 | |
| Sutherland Everett Rand | director, officer: Chief Executive Officer | 2024-10-10 | 5.69 | 2024-10-10 | |
| Sutherland Everett Rand | director, officer: Chief Executive Officer | 2024-10-10 | 6.59 | 2024-10-10 | |
| Chimovits Erez | director, 10 percent owner: | 2024-10-10 | 0 | 2024-10-10 | |
| Chimovits Erez | director, 10 percent owner: | 2024-10-10 | 0 | 2024-10-10 | |
| Chimovits Erez | director, 10 percent owner: | 2024-10-10 | 0 | 2024-10-10 | |
| Chimovits Erez | director, 10 percent owner: | 2024-10-10 | 0 | 2024-10-10 | |
| Beckman Daniella | 2024-10-10 | 0 | 2024-10-10 | ||
| Houghton Adam | officer: Chief Business Officer | 2024-10-10 | 3.45 | 2024-10-10 | |
| Houghton Adam | officer: Chief Business Officer | 2024-10-10 | 4.27 | 2024-10-10 | |
| Houghton Adam | officer: Chief Business Officer | 2024-10-10 | 4.87 | 2024-10-10 | |
| Houghton Adam | officer: Chief Business Officer | 2024-10-10 | 6.59 | 2024-10-10 | |
| Ruddy Marcella K. | director | 2024-10-10 | 3.45 | 2024-10-10 | |
| Ruddy Marcella K. | director | 2024-10-10 | 4.27 | 2024-10-10 | |
| Ruddy Marcella K. | director | 2024-10-10 | 4.87 | 2024-10-10 | |
| Ratcliffe Liam | 2024-10-10 | 0 | 2024-10-10 | ||
| Deykin Aaron | officer: Chief Medical Officer | 2024-10-10 | 3.45 | 2024-10-10 | |
| Deykin Aaron | officer: Chief Medical Officer | 2024-10-10 | 4.27 | 2024-10-10 | |
| Deykin Aaron | officer: Chief Medical Officer | 2024-10-10 | 4.87 | 2024-10-10 | |
| Deykin Aaron | officer: Chief Medical Officer | 2024-10-10 | 6.59 | 2024-10-10 | |
| Fleming Harold Edward | 2024-10-10 | 0 | 2024-10-10 | ||
| ORBIMED ADVISORS LLC | director, 10 percent owner: | 2024-10-10 | 0 | 2024-10-10 | |
| ORBIMED ADVISORS LLC | director, 10 percent owner: | 2024-10-10 | 0 | 2024-10-10 | |
| Renaud Ronald C JR | director | 2024-10-10 | 3.45 | 2024-10-10 | |
| Renaud Ronald C JR | director | 2024-10-10 | 4.87 | 2024-10-10 | |
| Renaud Ronald C JR | director | 2024-10-10 | 6.59 | 2024-10-10 | |
| Renaud Ronald C JR | director | 2024-10-10 | 4.27 | 2024-10-10 | |
| ORBIMED ADVISORS LLC | director, 10 percent owner: | 2024-10-10 | 0 | 2024-10-10 | |
| ORBIMED ADVISORS LLC | director, 10 percent owner: | 2024-10-10 | 0 | 2024-10-10 | |
| GRAY MICHAEL | officer: CFO and COO | 2024-10-10 | 5.69 | 2024-10-10 | |
| AI Upstream LLC | 10 percent owner | 2024-10-10 | 0 | 2024-10-10 | |
| AI Upstream LLC | 10 percent owner | 2024-10-10 | 0 | 2024-10-10 |