NASDAQ : UPB

Upstream Bio, Inc.

$7.09 USD

-$0.35 (-4.7%)

Volume
612.07K
Average Volume
593.6K
Market Capitalization
$385.84M
P/E Ratio
-2.44
Dividend Yield
0.00%
Price Target
$20.00
Year High
$33.68
Year Low
$5.85
Day High
Day Low
Payout Ratio
$0.00
Current Ratio
$27.99
Company Overview

NASDAQ

E. Rand Sutherland

Biotechnology

Healthcare

UPB

75

US

USD

781 208 2466

91678A107

0002022626

Liquidity Metrics

0.00

27.99

27.99

7.95

0.00

Sales & Valuation

$2.85M

122.18

1.43

-2.83

-2.50

Profitability

-$2.66

-$143.44M

-4955.67%

-4955.67%

-48.40%

-55.66%

P/E Metrics

-2.44

0.08

0.08

Analyst Price Target & Rating

$20.00

$25.00

$15.00

Sell

2/5

3 Analysts

-64.55%

Financial Health Scores

15.16

2/9

$302.61M

$318.05M

$14.06M

-$156.76M

Key Metrics (TTM)

$309.27M

93.10

-1.98

23.14

-43.82%

-56.36%

-38.78%

-34.58%

-12624 days

Company Executives
Name Title
Adam Houghton Chief Business Officer
Meggan Buckwell Director of Corporate Communications & Investor Relations
Mersedeh Miraliakbari Senior Vice President of Regulatory Affairs & Quality
Stacy Price Chief Technology Officer
Lisa Fiering Senior Vice President of People & Culture
Michael Paul Gray Chief Financial Officer & Chief Operating Officer
Aaron Deykin Chief Medical Officer and Head of Research & Development
Fang Xie Vice President & Head of Biometrics
E. Rand Sutherland Chief Executive Officer & Director
Allison Ambrose Senior Vice President, General Counsel & Secretary
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About Upstream Bio, Inc. (NASDAQ:UPB) Stock

Upstream Bio, Inc. is a biotechnology company in the clinical development stage, dedicated to innovating therapies for inflammatory conditions, particularly those affecting the severe respiratory system. Its pipeline notably features verekitug, a monoclonal antibody designed to selectively target and suppress the thymic stromal lymphopoietin receptor. Beyond this, the company is actively developing treatments for severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Established in 2021, Upstream Bio maintains its operational base in Waltham, Massachusetts. ...

Upstream Bio, Inc. (UPB) Reports Q2 Loss, Tops Revenue Estimates

2026-08-11 09:36:06

Upstream Bio, Inc. (UPB) came out with a quarterly loss of $0.73 per share versus the Zacks Consensus Estimate of a loss of $0.78. This compares to a loss of $0.74 per share a year ago.

Upstream Bio, Inc. (UPB) Upgraded to Buy: What Does It Mean for the Stock?

2026-07-14 13:01:07

Upstream Bio, Inc. (UPB) has been upgraded to a Zacks Rank #2 (Buy), reflecting growing optimism about the company's earnings prospects. This might drive the stock higher in the near term.

Fannie Mae Announces the Results of its Thirty-sixth Reperforming Loan Sale Transaction

2026-06-29 15:00:00

Fannie Mae Announces the Results of its Thirty-sixth Reperforming Loan Sale Transaction PR Newswire WASHINGTON,

Upstream Bio Presents New Responder Analyses Demonstrating Clinically Meaningful Improvements in CRSwNP in Significant Majority of Participants Treated with Verekitug in the Phase 2 VIBRANT Trial at EAACI 2026

2026-06-14 10:00:00

– Verekitug, administered once every three months, led to clinically meaningful improvements in nasal polyp score (NPS) in approximately 80% of participants –

KBRA Assigns Preliminary Ratings to OBX 2026-AHC2 Trust

2026-06-12 17:07:00

NEW YORK--(BUSINESS WIRE)-- #creditratingagency--KBRA assigns preliminary ratings to 65 classes of mortgage pass-through notes from OBX 2026-AHC2 Trust, a prime agency-eligible RMBS transaction sponsored by Onslow Bay Financial LLC, that is fully originated and serviced by AmeriHome Mortgage Company, LLC (AmeriHome). This transaction is comprised of 599 residential mortgages with an aggregate unpaid principal balance (UPB) of approximately $340.0 million as of the June 1, 2026 cut-off date. The underlying collateral.

Upstream Bio, Inc. (UPB) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript

2026-06-10 13:52:10

Upstream Bio, Inc. (UPB) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript

Upstream Bio to Showcase Additional Efficacy Data from the Phase 2 VIBRANT Trial of Verekitug in CRSwNP in Oral Session at EAACI 2026

2026-06-08 07:00:00

WALTHAM, Mass., June 08, 2026 (GLOBE NEWSWIRE) -- Upstream Bio, Inc. (Nasdaq: UPB), a clinical-stage company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders, today announced that additional data from its Phase 2 VIBRANT trial of verekitug in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) will be presented in an oral session at the European Academy of Allergy and Clinical Immunology (EAACI) 2026 Congress in Istanbul, Turkey, on Sunday, June 14, 2026.

Upstream Bio to Present at the Goldman Sachs 47th Annual Global Healthcare Conference

2026-06-03 07:00:00

WALTHAM, Mass., June 03, 2026 (GLOBE NEWSWIRE) -- Upstream Bio, Inc. (Nasdaq: UPB), a clinical-stage company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders, today announced that Rand Sutherland, MD, Chief Executive Officer of Upstream Bio, will participate in a fireside chat at the Goldman Sachs 47th Annual Global Healthcare Conference on Wednesday, June 10, 2026, at 10:40 a.m.

Frequently Asked Questions

What is the current Upstream Bio, Inc. (UPB) stock price?

Upstream Bio, Inc.(NASDAQ:UPB) stock price is $7.09 in the last trading session. During the trading session, UPB stock reached the peak price of $33.68 while $5.85 was the lowest point it dropped to. The percentage change in UPB stock occurred in the recent session was --4.7% while the dollar amount for the price change in UPB stock was -$0.35.

UPB's industry and sector of operation?

The NASDAQ listed UPB is part of Biotechnology industry that operates in the broader Healthcare sector.

Who are the executives of UPB?

Adam Houghton | Chief Business Officer
Meggan Buckwell | Director of Corporate Communications & Investor Relations
Mersedeh Miraliakbari | Senior Vice President of Regulatory Affairs & Quality
Stacy Price | Chief Technology Officer
Lisa Fiering | Senior Vice President of People & Culture

How many employees does UPB have?

Number of UPB employees currently stands at 75. UPB operates from 890 Winter Street, Waltham, MA 02451, US.

Link for UPB official website?

Official Website of UPB is: https://upstreambio.com

How do I contact UPB?

UPB could be contacted at phone #781 208 2466 and can also be accessed through its website. UPB operates from 890 Winter Street, Waltham, MA 02451, US.

How many shares of UPB are traded daily?

The average number of UPB shares traded daily for last 3 months was 593.6K.

What is the market cap of UPB currently?

The market value of UPB currently stands at $385.84M with its latest stock price at $7.09