Is Upstream Bio, Inc. (UPB) a Buy, Sell, or Hold?
NASDAQ : UPB
Upstream Bio, Inc. — Institutional Ownership
$7.05 USD
-$0.04 (-0.56%)
- Volume
- 21.99K
- Average Volume
- 593.6K
- Market Capitalization
- $383.66M
- P/E Ratio
- -2.43
- Dividend Yield
- 0.00%
- Price Target
- $20.00
- Year High
- $33.68
- Year Low
- $5.85
- Day High
- —
- Day Low
- —
- Payout Ratio
- $0.00
- Current Ratio
- $27.99
Institutional Ownership Summary
Institutional Ownership %
%
Investors Holding
change: 0.0 | last:
Increased Positions
change: 0.0 | last:
Reduced Positions
change: 0.0 | last:
New Positions
change: 0.0 | last:
Sold Positions
change: 0.0 | last:
Total Calls
-
Total Puts
-
Put-Call Ratio
change: 0.0 | last:
Total Invested
-
Beneficial Ownership Filings
| Filing Date | Reporting Person | Amount Beneficially Owned | % of Class |
|---|---|---|---|
| 2026-07-30 | BlackRock, Inc. | 2.81M | 5.20% |
| 2026-05-15 | Decheng Capital Global Life Sciences Fund IV, L.P. | 2.72M | 5.00% |
| 2025-11-14 | HBM Healthcare Investments (Cayman) Ltd. | 2.2M | 4.10% |
| 2025-11-14 | TCG Crossover GP I, LLC | 2.12M | 3.90% |
| 2025-10-24 | Norges Bank | 2.88M | 5.30% |
| 2025-08-06 | FMR LLC | 7.94M | 14.80% |
| 2025-02-14 | TCG Crossover GP I, LLC | 2.8M | 5.20% |
| 2025-02-14 | Decheng Capital Global Life Sciences Fund IV, L.P. | 3.09M | 5.80% |
| 2025-02-13 | HBM Healthcare Investments (Cayman) Ltd. | 2.72M | 5.10% |
| 2025-02-12 | FMR LLC | 7.18M | 13.40% |
| 2024-11-07 | FMR LLC | 6.07M | 11.82% |
| 2024-11-07 | Abigail P. Johnson | 6.07M | 11.82% |
| 2024-10-22 | AI Upstream LLC | 5.49M | 10.70% |
| 2024-10-22 | Access Industries Holdings LLC | 5.49M | 10.70% |
| 2024-10-22 | Access Industries Management, LLC | 5.49M | 10.70% |
| 2024-10-22 | AI Biotechnology LLC | 5.49M | 10.70% |
| 2024-10-22 | Len Blavatnik | 5.49M | 10.70% |
| 2024-10-18 | BCLS Fund III Investments, LP | 2.3M | 4.30% |
| 2024-10-17 | OrbiMed Advisors Israel II Limited | 1.14M | 2.20% |
| 2024-10-17 | OrbiMed Advisors LLC | 4.55M | 8.90% |
| 2024-10-17 | OrbiMed Israel GP II, L.P. | 1.14M | 2.20% |
| 2024-10-17 | OrbiMed Capital GP VIII LLC | 4.55M | 8.90% |
UPB Enterprise Value History
Annual
| Date | Stock Price | Shares Outstanding | Market Cap | Cash & Equivalents | Total Debt | Enterprise Value |
|---|---|---|---|---|---|---|
| 2025-12-31 | $27.15 | 53.85M | $1.46B | $101.58M | $1.27M | $1.36B |
| 2024-12-31 | $16.44 | 51.34M | $844.06M | $325.89M | $1.83M | $520M |
| 2023-12-31 | $22.00 | 36.32M | $799.11M | $25.83M | $45000 | $773.33M |
| 2022-12-31 | $22.00 | 36.32M | $799.11M | $17.05M | $94000 | $782.16M |
Quarterly
| Date | Stock Price | Shares Outstanding | Market Cap | Cash & Equivalents | Total Debt | Enterprise Value |
|---|---|---|---|---|---|---|
| 2026-06-30 | $6.92 | 54.57M | $377.61M | $79.4M | $954K | $299.17M |
| 2026-03-31 | $9.00 | 54.33M | $488.99M | $96.72M | $1.11M | $393.38M |
| 2025-12-31 | $27.15 | 54.24M | $1.47B | $101.58M | $1.27M | $1.37B |
| 2025-09-30 | $18.81 | 53.93M | $1.01B | $72.16M | $1.42M | $943.7M |
| 2025-06-30 | $10.98 | 53.77M | $590.4M | $45.46M | $1.56M | $546.51M |
| 2025-03-31 | $6.12 | 53.62M | $328.14M | $71.31M | $1.7M | $258.53M |
| 2024-12-31 | $16.44 | 51.34M | $844.06M | $325.89M | $1.83M | $520M |
| 2024-09-30 | $22.00 | 51.34M | $1.13B | $32.95M | $1.94M | $1.1B |
| 2024-06-30 | $22.00 | 51.34M | $1.13B | $47.34M | -$ | $1.08B |
| 2024-03-31 | $22.00 | 51.34M | $1.13B | -$ | -$ | $1.13B |
| 2023-12-31 | $22.00 | 36.32M | $799.11M | $25.83M | $45000 | $773.33M |
| 2023-09-30 | $22.00 | 36.32M | $799.11M | -$ | -$ | $799.11M |